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Minimally Invasive Gynecologic Surgery

Laparoscopic
Hysterectomy

Surgical Technique, Anatomy & Clinical Decision-Making

Specialty Gynecologic Surgery
Level Postgraduate CME
Slides 18 Comprehensive
Evidence-Based Practice
02

Overview & Definition

What is Laparoscopic Hysterectomy?

Surgical removal of the uterus performed through small abdominal incisions (5–12 mm) using a laparoscope and specialized instruments, with CO₂ pneumoperitoneum providing the operative field.

600K+ Hysterectomies/year (USA)
~70% Now performed minimally invasively
2–3 days Average hospital stay
Gold Standard: ACOG and AAGL recommend the minimally invasive approach as the preferred route for hysterectomy when technically feasible, citing superior outcomes over open surgery.

Advantages Over Open Surgery

Reduced blood loss — avg. 100–200 mL vs 400–500 mL (open)
Shorter hospital stay — 1–2 days vs 3–5 days
Faster recovery — return to activity in 2–3 weeks vs 6–8 weeks
Lower wound complication rate — reduced SSI, hernia risk
Less post-operative pain — reduced opioid requirement
Better visualization — magnified HD view of operative field
Cosmesis — minimal scarring, improved patient satisfaction
03

Indications for Surgery

Benign Conditions

🔴
Uterine Fibroids (Leiomyomata)

Symptomatic fibroids causing menorrhagia, bulk symptoms, or failed conservative management. Most common indication (~40%).

🟠
Endometriosis / Adenomyosis

Severe pelvic pain, dysmenorrhea, dyspareunia unresponsive to medical therapy. Adenomyosis causing heavy bleeding.

🟡
Abnormal Uterine Bleeding (AUB)

Refractory menorrhagia or metrorrhagia after failed endometrial ablation or medical management.

🟢
Uterovaginal Prolapse

Symptomatic pelvic organ prolapse requiring surgical correction with concurrent hysterectomy.

🔵
Chronic Pelvic Pain

Intractable pelvic pain with identifiable uterine pathology after exhaustive conservative measures.

Oncologic Indications

Stage I–II
Endometrial Carcinoma — Laparoscopic staging + hysterectomy with BSO and lymph node assessment
CIN III
Cervical Intraepithelial Neoplasia — High-grade dysplasia failing conservative treatment
Prophylactic
BRCA1/2 Mutation Carriers — Risk-reducing salpingo-oophorectomy ± hysterectomy
Benign
Ovarian Cysts / Masses — Complex adnexal pathology requiring definitive management
⚠ Note on Cervical Cancer: Radical laparoscopic hysterectomy for cervical cancer (Stage IB1) has shown inferior oncologic outcomes vs open surgery in the LACC trial (2018). Open approach preferred for invasive cervical cancer.
04

Contraindications

Absolute Contraindications

Inability to tolerate general anesthesia

Severe cardiopulmonary disease precluding Trendelenburg position and pneumoperitoneum

Uncorrected coagulopathy

Active bleeding disorder or anticoagulation that cannot be reversed perioperatively

Invasive cervical cancer (Stage IB+)

Open radical hysterectomy preferred per LACC trial evidence

Bowel obstruction / peritonitis

Active intra-abdominal infection or obstruction requiring open exploration

Relative Contraindications

~
Massive uterine size (>20 weeks)

Technically challenging; may require morcellation or conversion. Surgeon experience dependent.

~
Severe pelvic adhesions

Prior multiple laparotomies, PID, endometriosis stage IV — increased conversion risk

~
Morbid obesity (BMI >50)

Increased anesthetic risk; limited instrument reach; consider robotic assistance

~
Prior pelvic radiation

Tissue friability, poor healing, altered anatomy — higher complication risk

~
Suspected malignancy with morcellation risk

Avoid power morcellation; use contained extraction systems if needed

05

Types of Laparoscopic Hysterectomy

LSH
Laparoscopic Subtotal Hysterectomy
Uterine corpus removed laparoscopically; cervix retained. Avoids colpotomy. Faster procedure with lower vault dehiscence risk.
Cervix preserved Morcellation required Ongoing smears needed
LAVH
Laparoscopically Assisted Vaginal Hysterectomy
Laparoscopy used for upper pedicles (infundibulopelvic, round ligaments); remainder completed vaginally. Hybrid approach.
Hybrid technique Vaginal completion Useful for adhesions
RLH
Robot-Assisted Laparoscopic Hysterectomy
Da Vinci robotic platform provides 3D vision, wristed instruments, tremor filtration. Preferred for complex cases, obesity, prior surgery.
3D HD vision Wristed instruments Steep learning curve
Classification (Reich, 1989 → AAGL 2011): Type I–V based on extent of laparoscopic dissection. Type III (TLH) is the current standard of care at most centers.
06

Pre-operative Assessment & Workup

History & Examination

  • Complete menstrual & obstetric history
  • Prior abdominal/pelvic surgeries
  • Bimanual pelvic examination
  • Uterine size, mobility, adnexal masses
  • BMI, cardiopulmonary assessment
  • Cervical smear status (up to date)
  • Endometrial biopsy if AUB

Investigations

  • Bloods: FBC, coagulation, group & save, renal/liver function, HbA1c
  • Imaging: Pelvic USS (uterine size, fibroids, ovaries)
  • MRI pelvis: Complex pathology, suspected adenomyosis, deep endometriosis
  • Cystoscopy: If bladder involvement suspected
  • Urodynamics: Concurrent incontinence symptoms
  • ECG + Echo: Cardiac risk stratification

Pre-op Preparation

  • Consent: Risks, alternatives, conversion to open
  • Bowel prep: Not routinely required (ERAS protocol)
  • VTE prophylaxis: LMWH + TED stockings
  • Antibiotics: IV cefazolin 1g at induction
  • Foley catheter: Inserted after induction
  • GnRH agonists: Consider 3 months pre-op for large fibroids to reduce size and vascularity
  • Iron supplementation: Correct pre-op anaemia
07

Patient Positioning & Theatre Setup

Patient Positioning

30–40° Trendelenburg
↓ Head down
Bowel displaced cephalad
Modified lithotomy position — Allen stirrups, hips at 15° flexion, knees at 90°
30–40° Trendelenburg — displaces bowel from pelvis; monitor for shoulder pain, brachial plexus injury
Arms tucked — padded, neutral position; avoid hyperextension
Shoulder braces — anti-slip pads preferred over rigid braces (nerve injury risk)
Uterine manipulator — inserted vaginally after catheterization (Clermont-Ferrand, RUMI, VCare)

Theatre Setup

📺
Monitor Position

Two HD monitors at foot of table, at surgeon eye level. Scrub nurse on patient's left.

🔬
Laparoscopic Tower

HD camera system (4K preferred), CO₂ insufflator, light source, electrosurgical unit, vessel sealing device

Energy Sources

Monopolar diathermy, bipolar forceps, advanced vessel sealing (LigaSure™, Harmonic™ scalpel)

🩺
Anesthesia

General anesthesia with endotracheal intubation. TIVA preferred. Maintain CO₂ at 12–15 mmHg.

08

Instruments & Equipment

Access & Visualization

📷
Laparoscope

0° or 30° Hopkins rod lens, 10mm diameter. 4K HD camera head.

🔧
Veress Needle

Spring-loaded safety needle for initial CO₂ insufflation (Palmer's point or umbilical)

Trocars

5mm, 10mm, 12mm — bladed or bladeless (Optiview™). Primary 10–12mm umbilical port.

Dissection & Grasping

✂️
Laparoscopic Scissors

Curved Metzenbaum scissors for sharp dissection of peritoneum and adhesions

🤏
Grasping Forceps

Atraumatic bowel graspers, toothed tissue graspers for uterine manipulation

🔍
Suction-Irrigation

5mm suction-irrigator for haemostasis, field clearing, and hydrodissection

Energy & Haemostasis

Harmonic Scalpel™

Ultrasonic energy — simultaneous cutting and coagulation up to 5mm vessels. Minimal thermal spread.

🔥
LigaSure™ / EnSeal™

Advanced bipolar vessel sealing — reliable haemostasis of vessels up to 7mm diameter

🧵
Needle Drivers & Sutures

Laparoscopic needle drivers for vault closure. Barbed suture (V-Loc™) or Vicryl 0 on CT-1 needle.

Uterine Manipulation

🔄
Uterine Manipulator

VCare™, RUMI II™, or Clermont-Ferrand — provides anteversion, retroversion, and colpotomy cup delineation

💊
Colpotomizer Cup

Delineates vaginal fornix for safe colpotomy; maintains pneumoperitoneum during uterine removal

09

Port Placement & Trocar Configuration

U 12 5 5 5 Primary (Camera) L Working R Working Optional 4th Xiphoid Pubic symphysis

Port Configuration Details

PortSizeLocationPurpose
P110–12mmUmbilical / supra-umbilicalCamera port (primary)
P25mmLeft iliac fossa (2cm medial to ASIS)Left working port
P35mmRight iliac fossa (mirror of P2)Right working port
P4*5mmSuprapubic midlineOptional 4th port (large uterus)

Key Principles

Palmer's point entry (left subcostal, MCL) preferred in patients with prior midline surgery or suspected umbilical adhesions
Hasson open technique — safest primary entry; direct visualization of peritoneal entry
Triangulation principle — working ports should form 60° angle with camera for optimal ergonomics
Inferior epigastric vessels — transilluminate abdominal wall before lateral port insertion to avoid injury
CO₂ pressure: 12–15 mmHg; flow rate 1–2 L/min; monitor end-tidal CO₂
Step 1 of 5
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Peritoneal Entry & Initial Inspection

1
Pneumoperitoneum Establishment

Veress needle inserted at umbilicus (or Palmer's point). Confirm intraperitoneal placement: saline drop test, low opening pressure (<8 mmHg), free gas flow. Insufflate to 15 mmHg.

2
Primary Trocar Insertion

10–12mm umbilical trocar inserted with controlled thrust. Alternatively, Hasson open technique with purse-string suture for secure seal. Camera introduced.

3
360° Diagnostic Laparoscopy

Systematic inspection: liver, gallbladder, stomach, bowel, appendix, omentum, pelvic organs. Document adhesions, endometriosis, unexpected pathology. Assess feasibility.

4
Secondary Port Insertion

Under direct laparoscopic vision, insert 5mm working ports bilaterally in iliac fossae. Transilluminate to avoid inferior epigastric vessels. Confirm triangulation.

5
Uterine Manipulation

Assistant manipulates uterus via vaginal manipulator — anteversion for posterior dissection, retroversion for anterior. Confirm colpotomy cup position.

Anatomical Landmarks to Identify

Round ligaments bilaterally
Infundibulopelvic (IP) ligaments
Broad ligament anatomy
Ureter course (retroperitoneal)
Uterine vessels at pelvic sidewall
Bladder reflection anteriorly
Rectosigmoid posteriorly
Pouch of Douglas
⚠ Critical: Always identify the ureter before dividing any pedicle. The ureter runs 1–2 cm lateral to the uterine artery at the level of the internal os — "water under the bridge."
Step 2 of 5
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Uterine Manipulation & Bladder Dissection

1
Round Ligament Division

Grasp and divide round ligament bilaterally using energy device (LigaSure/Harmonic) at its midpoint. This opens the broad ligament and provides access to the retroperitoneal space.

2
Retroperitoneal Dissection & Ureter Identification

Open the broad ligament leaf. Develop the pararectal and paravesical spaces. Identify the ureter on the medial leaf of the broad ligament — confirm peristalsis. This is the most critical safety step.

3
IP Ligament / Ovarian Pedicle Management

If BSO planned: divide IP ligament (ovarian vessels) after confirming ureter is safe. If ovaries conserved: divide utero-ovarian ligament and fallopian tube close to uterus.

4
Anterior Peritoneal Incision (Bladder Flap)

Incise vesicouterine peritoneum transversely. Develop the vesicovaginal space using sharp and blunt dissection. Push bladder inferiorly off the cervix and upper vagina — expose the colpotomy cup.

5
Posterior Peritoneal Dissection

Open posterior broad ligament. Develop rectovaginal space if needed (especially in endometriosis). Identify and protect rectum and ureters posterolaterally.

Surgical Spaces Developed

Paravesical space — between bladder and pelvic sidewall
Pararectal space — between rectum and pelvic sidewall
Vesicovaginal space — anterior to vagina/cervix
Rectovaginal space — posterior to vagina
⚠ Bladder Injury Prevention: Ensure bladder is fully decompressed (Foley catheter). Hydrodissection with saline can help develop the vesicovaginal plane in difficult cases. Never use energy near the bladder wall.
Step 3 of 5
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Uterine Vessel Ligation

1
Skeletonization of Uterine Vessels

Dissect the uterine artery and vein from surrounding areolar tissue at the level of the internal os. The ureter must be visualized and displaced laterally before proceeding. "Skeletonize" the vessels for 1–2 cm.

2
Uterine Artery Ligation — Medial Approach

Apply energy device (LigaSure/Harmonic) directly on the uterine vessels at the level of the internal os, close to the uterus. Seal and divide. Confirm haemostasis. Repeat contralaterally.

3
Cardinal & Uterosacral Ligament Division

Divide the cardinal ligaments (Mackenrodt's) and uterosacral ligaments using energy device. These provide the main uterine support. Ensure ureter is safe — it runs close to the uterosacral ligament.

4
Haemostasis Check

Reduce pneumoperitoneum to 5–8 mmHg and inspect all pedicles for bleeding. Irrigate and aspirate. Apply additional energy or clips as needed before proceeding to colpotomy.

Vascular Anatomy — Key Relations

Uterine artery — branch of internal iliac (hypogastric) artery. Crosses ureter superiorly at level of internal os.
Uterine veins — drain into internal iliac vein. Multiple tributaries — ensure complete sealing.
Ovarian vessels (IP ligament) — arise from aorta (left) and renal vein (right). Divide if BSO planned.
⚠ Ureter Safety Rule: The ureter passes within 1–2 cm of the uterine artery. Always confirm ureter position before applying energy. If in doubt — open the retroperitoneum and directly visualize.
Step 4 of 5
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Colpotomy & Uterine Removal

1
Colpotomy (Vaginal Cuff Incision)

Using monopolar hook or energy device, incise the vaginal fornix circumferentially along the colpotomy cup of the uterine manipulator. The cup provides a safe guide and maintains pneumoperitoneum. Incise anteriorly first, then posteriorly.

2
Pneumoperitoneum Maintenance

Once vagina is entered, pneumoperitoneum is maintained by the colpotomy cup or by packing the vagina with a wet swab. Alternatively, use a vaginal occluder balloon. Prevent CO₂ loss.

3
Uterine Extraction

Uterus delivered vaginally by the assistant. For large uteri: in-situ morcellation within a contained bag system (FDA-approved), or bisection/coring technique. Ensure complete specimen retrieval.

4
Specimen Handling

Send uterus, cervix, and adnexa (if removed) for histopathological examination. Document weight, dimensions, and macroscopic findings. Frozen section if malignancy suspected intraoperatively.

Morcellation Considerations

⚠ FDA Warning (2014, updated 2020): Power morcellation contraindicated if uterine malignancy suspected — risk of disseminating occult cancer. Contained bag systems (PneumoLiner™) mitigate but do not eliminate risk.
Alternatives to morcellation:
  • Vaginal delivery (preferred if uterus <12 weeks size)
  • Mini-laparotomy extraction (Pfannenstiel incision)
  • In-bag morcellation with contained system
  • Bisection / coring technique vaginally
Step 5 of 5
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Vaginal Vault Closure

1
Vault Inspection & Haemostasis

Inspect vaginal cuff edges for bleeding. Apply bipolar diathermy to bleeding points. Irrigate pelvis thoroughly. Reduce pneumoperitoneum to 5 mmHg to check for venous ooze.

2
Laparoscopic Vault Suture

Close vaginal vault laparoscopically using continuous or interrupted sutures. Options: Vicryl 0 on CT-1 needle (figure-of-8 or running), or barbed suture (V-Loc™ 0) for easier intracorporeal suturing. Include full thickness of vaginal wall.

3
Uterosacral Ligament Incorporation

Incorporate uterosacral ligament stumps into the vault closure angles to provide apical support and reduce risk of vault prolapse. This is the McCall culdoplasty principle applied laparoscopically.

4
Final Inspection & Port Closure

Systematic inspection of all pedicles, vault, bladder, ureters, and bowel. Irrigate until clear. Reduce CO₂ and remove ports under vision. Close 10–12mm port fascial defects (Vicryl 1 J-needle). Skin closure.

Vault Closure Techniques Compared

Laparoscopic Closure
✓ Better visualization of vault angles
✓ Incorporates uterosacral ligaments
✓ Lower vault dehiscence rate
Vaginal Closure
✓ Faster technique
✓ Familiar to most surgeons
✓ Adequate for straightforward cases
Vault Dehiscence Rate: ~1–4% overall. Risk factors: energy use at vault, poor suture technique, early intercourse, infection. Presents as vaginal bleeding/discharge with bowel evisceration in severe cases — surgical emergency.
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Intraoperative Complications & Management

🩸
Haemorrhage Incidence: 1–3%

Causes: Uterine vessel injury, IP ligament bleeding, port-site vessel injury, trocar injury to iliac vessels

Management: Direct pressure, additional energy/clips, suture ligation. If uncontrolled → immediate conversion to laparotomy. Activate massive transfusion protocol.

🔴
Ureter Injury Incidence: 0.3–1%

Causes: Thermal injury during vessel sealing, suture ligation, kinking, transection. Most common at uterine artery crossing and uterosacral ligament.

Management: Intraoperative: ureteric stent, primary repair, ureteroneocystostomy. Postoperative: CT urogram, urology referral, percutaneous nephrostomy if needed.

💧
Bladder Injury Incidence: 0.5–2%

Causes: Bladder dissection, energy injury, trocar entry in undrained bladder

Management: Intraoperative repair in 2 layers (Vicryl 2-0). Foley catheter 7–14 days. Cystogram before removal.

🟠
Bowel Injury Incidence: 0.1–0.5%

Causes: Trocar entry, adhesiolysis, thermal spread from energy devices

Management: Small bowel: primary repair or resection. Colon: primary repair ± diversion. General surgery involvement. Delayed thermal injuries present 3–7 days post-op.

🔄
Conversion to Laparotomy Rate: 2–5%

Indications: Uncontrolled bleeding, dense adhesions, poor visualization, organ injury, equipment failure

Principle: Conversion is NOT a failure — it is sound surgical judgment. Consent patients pre-operatively.

Gas Embolism / Emphysema Rare: <0.1%

Causes: Veress needle in vessel, excessive pressure, prolonged surgery

Management: Immediate desufflation, Durant's maneuver (left lateral decubitus), 100% O₂, aspiration via CVP line. Anaesthetic emergency.

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Post-operative Care & Recovery

ERAS Protocol (Enhanced Recovery)

Day 0 (Op Day)
Early mobilization within 4–6 hours
Oral fluids when alert
Remove urinary catheter at 6–12 hours
Multimodal analgesia: paracetamol + NSAID + opioid PRN
Anti-emetics prophylactically
Day 1–2
Regular diet resumed
Discharge if pain controlled, mobile, tolerating diet
Continue LMWH for 28 days (cancer cases) or 7 days (benign)
Wound check, discharge analgesia
Week 2–6
Pelvic rest for 6 weeks (no intercourse, tampons, heavy lifting)
Return to light activity at 2 weeks
Return to work: 2–4 weeks (desk job), 4–6 weeks (physical)
Outpatient review at 6 weeks

Post-op Complications to Monitor

24–48h
Primary haemorrhage — vault bleeding, pedicle haemostasis failure. Monitor Hb, vital signs.
3–7 days
Delayed bowel injury — thermal injury presenting as peritonitis. High index of suspicion for abdominal pain + fever.
1–2 weeks
Vault dehiscence — vaginal bleeding, discharge, bowel evisceration. Surgical emergency.
1–3 weeks
Ureteric fistula / obstruction — flank pain, haematuria, urinary leakage. CT urogram + urology.
Any time
VTE (DVT/PE) — highest risk in first 4 weeks. LMWH prophylaxis essential. Mobilize early.
Hormonal Considerations: If bilateral oophorectomy performed in premenopausal women — initiate HRT immediately post-op (unless contraindicated) to prevent surgical menopause symptoms and long-term cardiovascular/bone risks.
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Outcomes & Evidence Base

Key Outcome Data

OutcomeLaparoscopicOpen
Blood loss (mL)100–200400–500
Hospital stay (days)1–23–5
Return to work (weeks)2–36–8
Wound infection (%)0.5–1%3–5%
Urinary tract injury (%)0.5–1%0.3–0.5%
Conversion rate (%)2–5%N/A
Patient satisfactionHigherLower

Landmark Trials

eVALuate Trial (2004)

Laparoscopic vs open/vaginal hysterectomy. Laparoscopic: longer OR time but faster recovery, less pain, better QoL.

LACC Trial (2018)

Minimally invasive vs open radical hysterectomy for cervical cancer. Open surgery superior — MIS associated with lower disease-free survival.

Learning Curve & Competency

20–50
Cases to achieve basic competency (TLH)
100+
Cases for advanced laparoscopic proficiency
AAGL
Fellowship training recommended for complex cases

Robotic vs Conventional Laparoscopic

Robotic advantages:
  • 3D HD visualization
  • Wristed instruments (7 degrees of freedom)
  • Tremor filtration
  • Shorter learning curve for complex cases
Robotic disadvantages:
  • Higher cost ($2,000–3,000 per case)
  • Longer setup time
  • No haptic feedback
  • Limited availability
AAGL Position Statement: Vaginal hysterectomy is the preferred approach when feasible. When vaginal approach is not possible, laparoscopic hysterectomy is preferred over open abdominal hysterectomy.
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References & Further Reading

Guidelines & Consensus Statements

1.
AAGL Advancing Minimally Invasive Gynecology Worldwide. AAGL Position Statement: Route of Hysterectomy to Treat Benign Uterine Disease. J Minim Invasive Gynecol. 2011;18(1):1-3.
2.
ACOG Committee Opinion No. 701. Choosing the Route of Hysterectomy for Benign Disease. Obstet Gynecol. 2017;129(6):e155-e159.
3.
NICE Guideline NG121. Heavy Menstrual Bleeding: Assessment and Management. National Institute for Health and Care Excellence. 2018 (updated 2021).
4.
FDA Safety Communication. Laparoscopic Power Morcellators. U.S. Food and Drug Administration. Updated 2020.

Landmark Clinical Trials

5.
Garry R, et al. eVALuate study: two parallel randomised trials, one comparing laparoscopic with abdominal hysterectomy, the other comparing laparoscopic with vaginal hysterectomy. BMJ. 2004;328(7432):129.
6.
Ramirez PT, et al. Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer (LACC Trial). N Engl J Med. 2018;379(20):1895-1904.

Surgical Technique References

7.
Reich H, DeCaprio J, McGlynn F. Laparoscopic hysterectomy. J Gynecol Surg. 1989;5(2):213-216. [Original description of TLH]
8.
Donnez O, Donnez J. A series of 400 laparoscopic hysterectomies for benign disease: a single centre, single surgeon prospective study of complications confirming previous retrospective study. BJOG. 2010;117(6):752-755.
9.
Wattiez A, Soriano D, Cohen SB, et al. The learning curve of total laparoscopic hysterectomy: comparative analysis of 1647 cases. J Am Assoc Gynecol Laparosc. 2002;9(3):339-345.
10.
Sandberg EM, et al. Laparoscopic hysterectomy versus abdominal hysterectomy: a systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2017;96(10):1157-1165.

Textbooks

11.
Nezhat C, Nezhat F, Nezhat C. Nezhat's Video-Assisted and Robotic-Assisted Laparoscopy and Hysteroscopy. 4th ed. Cambridge University Press; 2013.
12.
Sutton C, Diamond MP. Endoscopic Surgery for Gynaecologists. 2nd ed. WB Saunders; 1998.